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MIF also has the ability to interact with embryonic stem cells (ESC). Wang et al. (2012) lose mild on this phenomenon by injecting undifferentiated ESC in to the spinal cord of wild-form mice and MIF knockout mice. Hind limb functionality was calculated utilizing the Basso Mouse Scale (BMS), which was at first regular for equally groups of mice. A
which is, stimulation of CD74 with exogenous MIF might cause an abnormal inflammatory state, as MIF is capable of stimulating CXCR2 and CXCR4 receptors Together with CD74. CXCR2 and CXCR4 receptors when activated encourage inflow of neutrophils and lymphocytes, respectively (63, sixty four). i absolutely sure didnt wish to be part of figuring out